An Adaptive Locally Connected Neuron Model: Focusing Neuron

This paper presents a new artificial neuron model capable of learning its receptive field in the topological domain of inputs. The model provides adaptive and differentiable local connectivity (plasticity) applicable to any domain. It requires no other tool than the backpropagation algorithm to learn its parameters which control the receptive field locations and apertures. This research explores whether this ability makes the neuron focus on informative inputs and yields any advantage over fully connected neurons. The experiments include tests of focusing neuron networks of one or two hidden layers on synthetic and well-known image recognition data sets. The results demonstrated that the focusing neurons can move their receptive fields towards more informative inputs. In the simple two-hidden layer networks, the focusing layers outperformed the dense layers in the classification of the 2D spatial data sets. Moreover, the focusing networks performed better than the dense networks even when 70$\%$ of the weights were pruned. The tests on convolutional networks revealed that using focusing layers instead of dense layers for the classification of convolutional features may work better in some data sets.Comment: 45 pages, a national patent filed, submitted to Turkish Patent Office, No: -2017/17601, Date: 09.11.201

Implicit Theories and Self-efficacy in an Introductory Programming Course

Contribution: This study examined student effort and performance in an introductory programming course with respect to student-held implicit theories and self-efficacy. Background: Implicit theories and self-efficacy shed a light into understanding academic success, which must be considered when developing effective learning strategies for programming. Research Questions: Are implicit theories of intelligence and programming, and programming-efficacy related to each other and student success in programming? Is it possible to predict student course performance using a subset of these constructs? Methodology: Two consecutive surveys (N=100 and N=81) were administered to non-CS engineering students in I\c{s}{\i}k University. Findings: Implicit theories and self-beliefs are interrelated and correlated with effort, performance, and previous failures in the course and students explain failure in programming course with "programming-aptitude is fixed" theory, and also that programming is a difficult task for themselves.Comment: Programming Education. 8 page

A Survey on Automated Diagnosis of Alzheimer's Disease Using Optical Coherence Tomography and Angiography

Retinal optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) are promising tools for the (early) diagnosis of Alzheimer's disease (AD). These non-invasive imaging techniques are cost-effective and more accessible than alternative neuroimaging tools. However, interpreting and classifying multi-slice scans produced by OCT devices is time-consuming and challenging even for trained practitioners. There are surveys on machine learning and deep learning approaches concerning the automated analysis of OCT scans for various diseases such as glaucoma. However, the current literature lacks an extensive survey on the diagnosis of Alzheimer's disease or cognitive impairment using OCT or OCTA. This has motivated us to do a comprehensive survey aimed at machine/deep learning scientists or practitioners who require an introduction to the problem. The paper contains 1) an introduction to the medical background of Alzheimer's Disease and Cognitive Impairment and their diagnosis using OCT and OCTA imaging modalities, 2) a review of various technical proposals for the problem and the sub-problems from an automated analysis perspective, 3) a systematic review of the recent deep learning studies and available OCT/OCTA datasets directly aimed at the diagnosis of Alzheimer's Disease and Cognitive Impairment. For the latter, we used Publish or Perish Software to search for the relevant studies from various sources such as Scopus, PubMed, and Web of Science. We followed the PRISMA approach to screen an initial pool of 3073 references and determined ten relevant studies (N=10, out of 3073) that directly targeted AD diagnosis. We identified the lack of open OCT/OCTA datasets (about Alzheimer's disease) as the main issue that is impeding the progress in the field.Comment: Submitted to Computerized Medical Imaging and Graphics. Concept, methodology, invest, data curation, and writing org.draft by Yasemin Turkan. Concept, method, writing review editing, and supervision by F. Boray Te

Computerised diagnosis of malaria

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Adaptive Convolution Kernel for Artificial Neural Networks

Many deep neural networks are built by using stacked convolutional layers of fixed and single size (often 3$\times$3) kernels. This paper describes a method for training the size of convolutional kernels to provide varying size kernels in a single layer. The method utilizes a differentiable, and therefore backpropagation-trainable Gaussian envelope which can grow or shrink in a base grid. Our experiments compared the proposed adaptive layers to ordinary convolution layers in a simple two-layer network, a deeper residual network, and a U-Net architecture. The results in the popular image classification datasets such as MNIST, MNIST-CLUTTERED, CIFAR-10, Fashion, and ``Faces in the Wild'' showed that the adaptive kernels can provide statistically significant improvements on ordinary convolution kernels. A segmentation experiment in the Oxford-Pets dataset demonstrated that replacing a single ordinary convolution layer in a U-shaped network with a single 7$\times$7 adaptive layer can improve its learning performance and ability to generalize.Comment: 25 page

Robust localization and identification of African clawed frogs in digital images

We study the automatic localization and identification of African clawed frogs (Xenopus laevis sp.) in digital images taken in a laboratory environment. We propose a novel and stable frog body localization and skin pattern window extraction algorithm. We show that it compensates scale and rotation changes very well. Moreover, it is able to localize and extract highly overlapping regions (pattern windows) even in the cases of intense affine transformations, blurring, Gaussian noise, and intensity transformations. The frog skin pattern (i.e. texture) provides a unique feature for the identification of individual frogs. We investigate the suitability of five different feature descriptors (Gabor filters, area granulometry, HoG,1 dense SIFT,2 and raw pixel values) to represent frog skin patterns. We compare the robustness of the features based on their identification performance using a nearest neighbor classifier. Our experiments show that among five features that we tested, the best performing feature against rotation, scale, and blurring modifications was the raw pixel feature, whereas the SIFT feature was the best performing one against affine and intensity modifications

Assessment of algorithms for mitosis detection in breast cancer histopathology images

The proliferative activity of breast tumors, which is routinely estimated by counting of mitotic figures in hematoxylin and eosin stained histology sections, is considered to be one of the most important prognostic markers. However, mitosis counting is laborious, subjective and may suffer from low inter-observer agreement. With the wider acceptance of whole slide images in pathology labs, automatic image analysis has been proposed as a potential solution for these issues. In this paper, the results from the Assessment of Mitosis Detection Algorithms 2013 (AMIDA13) challenge are described. The challenge was based on a data set consisting of 12 training and 11 testing subjects, with more than one thousand annotated mitotic figures by multiple observers. Short descriptions and results from the evaluation of eleven methods are presented. The top performing method has an error rate that is comparable to the inter-observer agreement among pathologists

Mitosis detection using generic features and an ensemble of cascade adaboosts

Context: Mitosis count is one of the factors that pathologists use to assess the risk of metastasis and survival of the patients, which are affected by the breast cancer. Aims: We investigate an application of a set of generic features and an ensemble of cascade adaboosts to the automated mitosis detection. Calculation of the features rely minimally on object-level descriptions and thus require minimal segmentation. Materials and Methods: The proposed work was developed and tested on International Conference on Pattern Recognition (ICPR) 2012 mitosis detection contest data. Statistical Analysis Used: We plotted receiver operating characteristics curves of true positive versus false positive rates; calculated recall, precision, F-measure, and region overlap ratio measures. Results: We tested our features with two different classifier configurations: 1) An ensemble of single adaboosts, 2) an ensemble of cascade adaboosts. On the ICPR 2012 mitosis detection contest evaluation, the cascade ensemble scored 54, 62.7, and 58, whereas the non-cascade version scored 68, 28.1, and 39.7 for the recall, precision, and F-measure measures, respectively. Mostly used features in the adaboost classifier rules were a shape-based feature, which counted granularity and a color-based feature, which relied on Red, Green, and Blue channel statistics. Conclusions: The features, which express the granular structure and color variations, are found useful for mitosis detection. The ensemble of adaboosts performs better than the individual adaboost classifiers. Moreover, the ensemble of cascaded adaboosts was better than the ensemble of single adaboosts for mitosis detection

Interactive Learning Based Nodule Detection in CT Lung Volumes

24th Signal Processing and Communication Application Conference (SIU) -- MAY 16-19, 2016 -- Zonguldak, TURKEYWOS: 000391250900482We present a novel method to automatically detect lung nodules in CT lung scans. Our method is generalized in the sense that it does not assume/depend a particular organ or a particular nodule type. hence it does not require an organ segmentation. We test our method in a challenging set (Anode09) that is comprised of low dose CT scans which include all types of nodules (solid, ground glass opacity, juxta-fissural, juxta-vascular) of less than 10mm in size. Our method produces 8 false positives per scan for true positive rate of 52%, which is comparable to the first 6 results from the contest.IEEE, Bulent Ecevit Univ, Dept Elect & Elect Engn, Bulent Ecevit Univ, Dept Biomed Engn, Bulent Ecevit Univ, Dept Comp Eng